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Assessing the antioxidant and metabolic effect of an alpha-lipoic acid and acetyl-L-carnitine nutraceutical

Meanwhile, B12 is a vital nutrient that supports energy production and nerve function

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393 Other novel targets P2Y14R, a member of the purinergic receptor family, has been shown to promote the transcription of RIPK1 through the cAMP/PKA/CREB signaling axis, thereby driving necrotic apoptosis of intestinal epithelial cells and exacerbating intestinal barrier disruption and inflammatory responses

In conclusion, multi-targeted nanomedicine delivery systems hold strong preclinical potential to provide a novel framework for advancing osteosarcoma treatment by precisely modulating the TME and eliciting durable antitumor immune responses