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Beyond its effects on T cell differentiation, GLP-1 also inhibits the migration of CD4 + T cells induced by chemokines by reducing the phosphorylation of PI3K, which is a key signaling pathway in the migration process [148]

Until one does, the correct statement is not that the combination is unsupported by strong evidence but that it is unstudied, which is a different and cleaner claim

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1, with 80 percent of those members taking it for weight loss

These encouraging results mean that prospective trials are needed to determine whether GLP-1 receptor agonists can be repurposed as gerotherapeutics, say the authors