You can read the full article at Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial Little is known about the effects of tirzepatide, a medication that stimulates both the glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, when added to insulin glargine for treating type 2 diabetes
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Poitou et al., Efficacy and safety of setmelanotide, a melanocortin-4 Recepr agonist, in patients with Bardet-Biedl syndrome and Alstrm syndrome: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial with an open-label period
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They both work in a similar way, but tirzepatide (Mounjaro) also mimics a second hormone, known as glucose-dependent insulinotropic polypeptide (GIP)