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In beta cell mitochondria, ROS produced during oxidative phosphorylation are detoxified by the glutathione redox system, which requires NADPH to maintain its redox state [92]

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De Luca P, Scarpa A, De Bonis E, et al

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Scientific References Long R3 insulin-like growth factor-1 (IGF-1) stimulates muscle cell hypertrophy Pharmacokinetics and tissue distribution of IGF-1 LR3 in preclinical models Long R3 insulin-like growth factor I (IGF-I) stimulates protein synthesis in muscle cells IGF-1 LR3: a potent analog with reduced binding to IGF-binding proteins