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The effect was statistically significant (P = 0.002), and benefits appeared within just 3-6 months of starting medication

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In the OASIS-1 study, 13% of participants (people with obesity without diabetes) receiving oral semaglutide 50 mg experienced altered skin sensation events compared to 1% with placebo - these events were generally mild to moderate in severity, occurred during dose escalation to the higher doses and resolved without requiring permanent treatment discontinuation [21]

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39 MAFLD Patients with MAFLD and an elevated fibrosis-4 index score or who have symptoms of gallbladder disease should undergo liver and gallbladder ultrasonography