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Translating a 15 mg/kg murine dose directly to humans underscores a severe translational gap in the source paper

The volatile oils/pungency have been removed, retaining primarily carotenoids and lipids

Notably, Nrf2 plays a dual protective role by both repressing neuroinflammatory signaling and promoting the transcription of antioxidant genes, establishing it as a compelling therapeutic target in neurodegenerative disorders [182, 183]

In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain

Enhancing Elastin Production Elastin is another important protein in the skin that allows it to maintain its shape and bounce back