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The underlying causes of allodynia are diverse and include peripheral neuropathy (commonly from diabetes), fibromyalgia, complex regional pain syndrome, migraine headaches, and postherpetic neuralgia following shingles

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GLP-1 receptor agonists in heart failure GLP-1 receptor agonists have demonstrated favorable cardiovascular effects in patients with T2DM and obesity as meta-analyses suggest a reduction in hospitalization for incident or new-onset HF of approximately 18%, alongside reductions in major adverse cardiovascular events [6, 14, 15]