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1,6 While specific data vary by product and region, the general expectation is: Mid-2020s - early 2030s: foundational peptide patents expire Late 2020s - mid-2030s: formulation and device patents phase out Ongoing regulatory exclusivities (e.g., data exclusivity) may further delay competition

CMAJ, 196 (43), E1413

The findings that the GLP-1RA liraglutide (50 g/kg) improved glucose tolerance as well as fasting blood glucose levels and increased insulin secretion in Kcnj11 / mice corroborate this conclusion (Figure 2E and Supplemental Figure 2C)

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