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Int J Nurs Stud 78:3743

GLP-1 medications work by overriding the body natural weight regulation system, which is powerful and persistent

however, the luciferase reporter assay clarified the suppressive role of CBX3 on CUL3 transcription, suggesting that CBX3-upregulated NRF2 expression by inhibiting CUL3 transcription and preventing CUL3-induced NRF2 degradation