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Abbreviations AT: As-treated CEA: Cost-effectiveness analysis CPI: Consumer price index CVD: Cardiovascular disease GDP: Gross domestic product GLA: Glucose-lowering agent GLP-1RA: GLP-1 receptor agonist HR: Hazard ratio ICER: Incremental cost-effectiveness ratio ITT: Intention-to-treated MACE: Major adverse cardiovascular event NHI: National Health Insurance NHIRD: National Health Insurance Research Database NNT: Number needed to treat OOP: Out-of-pocket QALY: Quality-adjusted life year T2D: Type 2 diabetes WTP: Willingness-to-pay References American Diabetes Association

For skin conditions, KPV modulates the same NF-kB pathway in dermal cells, calming inflammatory responses associated with redness, irritation, and delayed healing

GHK-Cu complements this by enhancing tissue repair, collagen synthesis, and antioxidant protection

OPITAC is a tri-peptide composed of glutamic acid, cysteine, and glycine