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Memantine, a clinically well-tolerated NMDAR antagonist with low affinity and rapid off-rate kinetics, can selectively block open channels and mitigate excitotoxicity while preserving normal glutamatergic transmission [202]
A previous history of vitiligo can also make a patient more vulnerable to a drug-induced extension of their pigment loss
When combined with glutathione, the stability and effectiveness of vitamin C are enhanced, allowing for longer-lasting and visible results
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