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By inhibiting NNMT, 5-Amino-1MQ prevents the breakdown of nicotinamide, which in turn increases the intracellular pool of NAD+

Although conceptual and functional overlap exists, this distinction is important because the two categories are subject to different regulatory pathways and evidentiary requirements

J., Eun, H

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So the practical selectivity gap between ipamorelin and sermorelin is narrower than most comparison articles imply