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10.1016/j.physbeh.2012.04.004 10 BezinJ.GouverneurA.PnichonM.MathieuC.GarrelR.Hillaire-BuysD.et al (2023)

GI symptoms resurface: Nausea, constipation, and diarrhea commonly return during tirzepatide initiation, consistent with starting any new GLP-1 treatment

What it means for private plans For employer plan sponsors, the report frames GLP-1 receptor agonists as a category where unit-price reductions from generics may be offset by: Higher patient volumes as access expands New indications added to existing molecules New, longer-acting and oral GLP-1 entrants in development Patients tracking coverage developments can review the generic semaglutide tracker, the insurance coverage checker, and the FAQ for additional context on Canadian pricing and plan rules

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Neuroinflammation and hypothalamic-pituitary dysfunction