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Practitioners report that most patients are willing to continue if they perceive any benefit
These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance
These actions translate to improved wound contraction, tissue remodeling, and even anti-aging effects in skin
It is targeted specifically at GH with minimal effect on other pituitary hormones like cortisol or prolactin, which gives it a clean side-effect profile
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