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We evaluate at the end of each cycle before deciding whether to repeat, adjust the dose, add a stack partner like TB-500, or transition to a maintenance approach

Key points Sporadic late-onset cerebellar ataxia (SLOCA) is a syndrome defined by subacute or chronic, progressive ataxia occurring after the age of 40 years in individuals with no family history of ataxia

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This pathway is also targeted by other PD-related factors

Basic & clinical pharmacology & toxicology , 118 (1), 7076