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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications that mimic the action of the naturally occurring GLP-1 hormone
On the other hand, glutathione-mimetic compounds or -glutamylcysteine (-GC), the limiting substrate for GSH biosynthesis, ameliorate brain pathologies and memory deficits in APP/PS1 63,64
Nonetheless, the most updated literature reports that -carotene supplementation or elevated blood -carotene levels may increase all-cause mortality and CVD risk [147, 148]
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Conclusion GLP-1RA therapy induces sustained receptor signaling while simultaneously reducing nutrient inflow, generating a systemic metabolic state characterized by chronic energy flux constriction
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