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Clinicians must also avoid intravenous administration in the presence of severe sino-atrial, atrioventricular, or intraventricular conduction block in the absence of functional pacemaker support, as well as in classic Adams-Stokes or Wolff-Parkinson-White syndromes, where suppression of accessory pathways may paradoxically precipitate fatal arrhythmias

A rare complication of this deficiency is optic neuropathy which results in progressive, bilateral, painless vision loss

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Dehydration exacerbates headaches, dizziness, and fatigue

Combining Both Methods In some cases, a combined approach is used