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Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes

Clin Transl Sci (2020) 13(1):13746

doi: 10.1038/s41580-018-0001-6 144 YaoRQRenCXiaZFYaoYM

(Rinvoq is in phase 3 trials for that indication.) For patients with multiple skin diseases, a single medication that can treat more than one condition at the same time could be an advantage, he says

Shima Hadidchi MDs practice with obesity, high blood pressure, type 2 diabetes, or high cholesterol