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[email protected] Chen, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Switching was defined as a change to a different GLP-1 between consecutive months (e.g., January to February 2025)

Only the HMB-supplemented group achieved statistically significant decreases in both fat mass and body fat percentage, demonstrating that HMB enhanced the body composition benefits of time-restricted eating beyond what the dietary pattern alone could deliver