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Berney DM, Looijenga LHJ, Idrees M, Oosterhuis JW, Rajpert-De Meyts E, Ulbright TM, Skakkebaek NE (2016) Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy

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Together, these examples show that with every use of chemical interventions off-targets for both the chemical and the solvent need to be ruled out for the proper interpretation of the results and mechanistic conclusions (Figure 3)

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