The two biggest factors are protein intake and resistance training
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If you are not on a medication and want metabolic support, the best-evidenced single ingredient is viscous fiber at 10 g or more daily (Ye et al., 2015), with berberine at 900 to 1,500 mg as the second option (Liang et al., 2019)
Ploy, MD, Qualified Peptide Therapy Doctor, Board Certified in Family Medicine, Regenerative & Longevity Medicine Specialist , licensed by the Medical Council of Thailand
The loss of muscle mass is a concern with weight loss, so protein intake is important to watch when a patient is taking such drugs, she said