The thinning of cell plates is explained by the compression of the hepatocytes in the cords adjacent to the dilated and congested sinusoids where the initial toxic effects probably occurred
Photographic documentation from month 1 versus month 4 to 6 typically shows measurable differences in density at areas of prior thinning, particularly the temples, crown, and frontal hairline
The intensity of the color varies based on B12 concentration, ranging from pale pink to deeper red
for instance, lighter skin became apparent after administering high doses for treating other diseases
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