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If weight falls but BFM is stable, water or muscle, not fat, is driving the scale change
Given that EtOH-induced mitochondrial dysfunction and ER stress are intimately involved in the pathogenesis of ALD, future studies to examine these pathways under the current experimental setting will provide important mechanistic information underlying the protection seen in GCLM KO mice
Glutathione acts as a powerful antioxidant and cleanses the liver of chemicals, hormones and pollutants
A plan may prefer one medication, require less documentation for one, or apply different step-therapy rules
Sulforaphane, a naturally occurring small molecule, activates the Nrf2-ARE pathway, upregulates antioxidant enzymes such as SOD and CAT, reduces ROS accumulation, and inhibits apoptosis
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