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Why trials are inconclusive for weight Many studies mix populations, use different doses, or add other supplements

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Sabry AA (2010)

A standard weight loss workup at our clinic includes: Fasting insulin and HOMA-IR, a direct measure of insulin resistance Hemoglobin A1C A full thyroid panel, including Free T3, Free T4, and Reverse T3 (not just TSH) Comprehensive sex hormone panels for both men and women Cortisol patterns Inflammatory markers Advanced lipid particle analysis A DEXA body composition scan to precisely measure fat mass, lean mass, visceral fat, and bone mineral density That diagnostic picture determines the protocol