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It was first identified in 1973 by biochemist Loren Pickart, who observed that plasma from younger donors caused older liver tissue to resume more youthful metabolic activity

Surface plasmon resonance studies demonstrate binding constants in the micromolar range, with the compound sequestering actin subunits through its -thymosin domain structure

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With developments in novel skin permeation enhancing methods such as microneedles and laser, copper compounds can potentially be used on skin for cosmeceutical or medicinal purposes 5,11,12