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Pillar 3: Nutrition (reduce glucotoxicity and lipotoxicity) Nutrition influences insulin resistance through energy balance, glucose exposure (glucotoxicity), lipid exposure (lipotoxicity), and gut hormone signalling
8,12,13 A meta-analysis by Ku and Chang 6 reported PASI improvement in both diabetic and nondiabetic groups (over the 6- to 12-week periods of the 4 prospective cohort studies analyzed), with nearly 35% achieving a 75% or greater improvement in PASI (PASI-75) from their respective baselines, and a proposed immunomodulatory mechanism
Research indexed on PubMed suggests DSIP has been studied in animal models in the contexts of response to stress, hormone modulation, and neuroprotection
doi: 10.1007/s11427-017-9229-1 216 ZhangL.ZhouW.ZhanL.HouS.ZhaoC.BiT.et al
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