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Features of SIPS include increased senescence-associated -galactosidase (SA--Gal) activity, appearance of senescence-associated heterochromatin foci (SAHF), cell growth arrest, and increased expression of senescence-associated genes 11,34

It is a popular compound in studies involving cellular aging, pineal gland function, and DNA repair mechanisms

Pain 1987

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Epithalon, a synthetic tetrapeptide based on pineal gland epithalamin, activates telomerase to maintain or extend telomeresthe protective caps on chromosomes that shorten with age