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A healthy microbial community can detoxify potentially neurotoxic substances, while dysbiosis may lead to the production of metabolites that cross the BBB and prime microglia, exacerbating neuroinflammatory responses (Sabahat et al., 2024

The supplement, developed by Nutrapharm, marks the first time a finished product containing Setria has received formal health authority approval in Chile a significant milestone for the ingredient and for Chile's rapidly growing dietary supplement market

Additionally, their under-development triple agonist, Retatrutide, has shown unprecedented weight loss effects in phase 2 clinical trials

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In in vivo experiments, using a leukemia mouse model, it was confirmed that HDACi pretreatment or oral administration of Citarabine (10 mg/kg) after infusion significantly reduced tumor burden and prolonged survival