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Kidney Protection (SURPASS-4) Heerspink HJL, Sattar N, Pavo I, et al
Pancreatitis (inflammation of the pancreas): Symptoms may include severe upper abdominal pain that doesnt go away, vomiting, and nausea Gallbladder disease (gallstones or gallbladder inflammation): Symptoms may include sudden and intense abdominal pain, nausea, vomiting, fever and chills Kidney problems: Changes in urination (either going more or less frequently), along with swelling in feet and ankles Hypersensitivity or allergic reactions (including anaphylaxis ): Shortness of breath, itching and swelling near the injection site, dizziness Diabetic retinopathy: People with type 2 diabetes and a history of diabetic retinopathy (a complication that affects the blood vessels in the eye) may experience worsening symptoms, including blurred vision, spots, and floaters : Symptoms include fast heartbeat, shakiness, dizziness, and confusion
As of March 25, 2026, retatrutide is not FDA approved
Girgis added that common side effects of Ozempic and Wegovy may trigger mental health side effects
I'm honest about the limits too
