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doi: 10.3389/fphys.2021.704290 Received 02 May 2021 Accepted 05 July 2021 Published 02 August 2021 Volume 12 - 2021 Edited by Luca Paolo Ardig, University of Verona, Italy Reviewed by Alfredo Santalla, Universidad Pablo de Olavide, Spain

For extra safety and peace of mind, aiming for a full week prior is even better, as alcohol is a known blood thinner

Caution is also advised in the following disease states: T2DM with suspected beta-cell failure consider insulin instead as GLP-1 and GIP analogues require beta cell function to be effective

Prescription weight-loss medication should not be used during pregnancy