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In those patients, addressing the underlying metabolic dysfunction first, through dietary intervention, GLP-1 therapy if indicated, or NAD+ support for cellular energy metabolism, is the clinical priority
11 In one clinical trial, the secoiridoids found in gentian, which are the compound responsible for that bitter taste, demonstrated both a higher response of GLP-1 and a significantly reduced appetite, evidenced by a 30% lower energy intake over the post-lunch period
Semaglutide has vaulted treatment of obesity and type 2 diabetes into a new era
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