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Place stronger human or clinical-context evidence toward the top and preclinical or regulatory-safety context below

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Studies show that while many patients experience substantial weight loss, average results outside of clinical trials can be more modestoften between 5% and 12% of body weight lost, depending on adherence and length of treatment

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To investigate the effects of pasireotide, H-89, ESI-09, and PTX, the cells were preincubated with pasireotide for 2.5 h, PTX for 46 h, H-89, and ESI-09, respectively