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Research Note: In a gene-array analysis of skin cells reviewed by Pickart and Margolina in the International Journal of Molecular Sciences (2018), GHK produced a change of 50% or greater in expression for 31.2% of the human genes tested, with about 59% of those genes upregulated and 41% suppressed (Pickart & Margolina, 2018)
Best Practices: Adhere to researched doses and routes, and monitor closelyhuman synergy data remain limited
So compared to the amount that we usually recommend
If a severe deficiency is found, a loading dose phase may be recommended, consisting of weekly injections for the first month
Researchers working with these compounds must comply with their institutional review board (IRB) requirements and applicable local and federal regulations
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