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Our work identifies SLC25A39 as an essential and regulated component of the mitochondrial GSH import machinery

However, the balance of Th1 cells with T helper 2 (Th2) cells needs to be tightly regulated

Some specialized medical diets like those used to treat certain metabolic disorders, including phenylketonuria, homocystinuria, and maple syrup urine disease, need to be supplemented with selenium to ensure optimal selenium status in patients (51)

This necessitates the development of small molecule inhibitors or mRNA delivery strategies to effectively harness its potential