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It is important to note, however, that in the case of medicines administered by injection, the MHRA is governed also by the foundational Medicines Act 1968 (now largely embodied in the Human Medicines Regulations 2012 )

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For researchers comparing blend versus separate vials, the math is meaningfully close, with the blend earning its small premium through ratio consistency, documentation simplification (one batch, one COA), and single-reconstitution efficiency