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Increased TMAO levels in addition to endothelial dysfunction, vascular aging, and oxidative stresses have been shown to cause thrombotic events and platelet excitability in humans, which in turn induce atherosclerosis [69, 72]

As with all investigational medicines, the safety profiles of cagrilintide and retatrutide are still being characterised through ongoing clinical trials

Antioxidants are molecules that neutralize harmful free radicals

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Roger Seheult, MD, a board-certified physician in internal medicine, pulmonary diseases, critical care, and sleep medicine at Loma Linda University