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Alterations in the volume of distribution and clearance resulting from other mechanisms of action (eg, reduced fat mass, changes in cytochrome P450 activity, and glomerular filtration rate) are key factors in determining pharmacokinetics
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Breast Cancer Res (2010) 12:R33.10.1186/bcr2587 147 TosovicABondesonAGBondesonLEricssonUBManjerJ
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