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These effects, in conjunction with potential sleep-enhancing benefits observed in patients with dementia treated with melatonin [214], provide a compelling rationale for hypothesizing that supplementing melatonin near bedtime may augment the glymphatic systems clearance function
Howard LJ et al
When aging commences, it has no shame
Current scientific consensus emphasizes that the primary criterion for probiotic selection is the specific clinical indicationwhether prophylactic, therapeutic, or adjunctivegiven the marked differences in efficacy exhibited by individual bacterial strains across distinct health objectives (517)
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