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Brain Res (1997) 752(1-2):2634
In a highdose semaglutide trial (7.2 mg weekly), participants lost about 20.7% of body weight in 72 weeks, with a substantial portion achieving up to 25% weight loss
This study demonstrates how database studies rooted in benchmarks against previously conducted randomized trials for the drugs of interest can produce complementary evidence to support expanded cardiovascular indications
The physiological changes that accompany GLP-1 therapy can create conditions where tiredness becomes more noticeable
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