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J Biochem Mol Toxicol 35(2):e22638 Snchez-Carranza JN, Daz JF, Redondo-Horcajo M et al (2018) Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation
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Copper peptides are naturally occurring complexes formed when small protein fragments, known as peptides, bind with copper ions in their divalent state
Additionally, early growth response factor 1 (EGR1) can bind to the promoter region of histone acetyltransferase EP300, upregulate EP300 expression, and enhance histone H3K27 acetylation, thereby inhibiting inflammation and apoptosis of PAECs and alleviating hypoxia-induced PAH (Yang et al., 2023)
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