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Some plaques can rupture causing thrombosis, potentially leading to the development of acute coronary syndrome (ACS) ( 1.2 Physiology of GLP-1 Glucagon like peptide-1 (GLP-1) is a peptide hormone produced in the intestinal tract by epithelial endocrine L-cells
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While bupropion works in the brain on dopamine and norepinephrine, tirzepatide works primarily in the gut, the pancreas, and appetite centers in the hypothalamus
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Some people taking tirzepatide experience nausea, vomiting, or diarrhea, especially in the early weeks of treatment
