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The FAE dimethyl fumarate (DMF) works at a number of levels, including blockage of signal transduction factors Nrf2, Nf-B, STAT1/STAT3, and HIF-1
doi: 10.1111/j.1749-6632.1968.tb14738.x [41] Shiga S & Cartotto R
It has low toxicity and is not a skin irritant, but its use in products is limited by a high price
& Nickerson, M
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