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Linear regression showed an inverse relationship between UA levels and TAU (OR = 0.610), progressive supranuclear palsy (OR = 0.626), AD (OR = 0.685) and frontotemporal dementia (OR = 0.577)
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For example, enhancing CMA could provide a specific route for the degradation of toxic proteins in neurodegenerative diseases, while inhibiting aggrephagy in cancer could lead to the accumulation of protein aggregates and induce cell death
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SCD1 catalyzes the desaturation of palmitic acid (16:0) into palmitoleic acid (16:1) and stearic acid (18:0) into oleic acid (18:1) 48
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