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Semaglutide dampens LPS-induced expression changes in glial cells and infiltration of peripheral neutrophils To map the cell-type-specific effects of LPS in combination with GLP-1 receptor activation, we performed single-nucleus RNA sequencing (snRNA-seq) of the hippocampus ( n = 71) spanning the acute (2 h, 24 h) and sub-chronic (5 days, 11 days) phases of inflammation (Fig

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In osteoarthritis, pain relief is often attributed to weight loss rather than direct analgesic effects, complicating the evaluation of GLP-1RAs efficacy