Key observation: All dose groups began at 0.5mg with gradual escalation over several weeks before reaching maintenance doses
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Underlying Health Conditions: Conditions like pernicious anemia, Crohns disease, or celiac disease can affect B12 absorption and necessitate ongoing treatment
References Philippou, A., Maridaki, M., Halapas, A., & Koutsilieris, M
PAT-1251 (IUPAC name: 3-((4-(aminomethyl)-6-chloropyridin-2-yl)oxy)phenyl)((3 R ,4 R )-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone, CAS# 2098884-53-6, structure see below) was obtained from Sundia Meditech Co.Ltd, and prepared in 0.5% methyl cellulose in DI water 41