First, published literature does not equal product-use guidance
On the other hand, considering the short distance between the C atom of cystathionine and the C4 atom of PLP in the cystathionine-bound external aldimine, the C hydrogen may directly move to the C4 atom without a base
Tryptophan hydroxylase is normally not saturated and as a result, an increase in dietary uptake of tryptophan will lead to increased brain serotonin content
The combination of these peptides creates a multi-layered regenerative network in which gene regulation, cytoskeletal dynamics, vascular support, matrix remodeling, and inflammation control converge
Applying a pro-remodeling signal during an active remodeling window is the intuitive appeal, and it mirrors the logic behind combining growth-factor or peptide serums with needling in clinical practice