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Phytochemicals such as, the Resveratrol (3,4,5-trihydroxy stilbene) and the Curcuminoids (with , -unsaturated carbonyl groups) are potential inducers of HO-1 expression through Nrf2/ antioxidant-responsive element (ARE) pathway 471,472
This unique combination enhances its ability to regulate appetite, promote satiety, and support weight loss more effectively than medications that only target one pathway
MC4R rs17782313 variations influence satiety signaling in the brain, meaning some people feel full faster while others require additional neurological support
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