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Reduced NAD+ availability impairs mitochondrial function, suppresses AMPK activation, and downregulates SIRT1-mediated fat oxidation genes

In plain English: It was designed to help the body burn fat without turning you into a bodybuilder from a 1987 fitness infomercial

The cells also become more resistant to lipolysis, the breakdown of stored fat for energy

For individuals with digestive sensitivities, those taking acid-reflux medications, or anyone on a plant-based (vegan/vegetarian) diet, absorbing enough B12 through food or pills is virtually impossible

[7] The reconstituted NAD+ is not preserved for long periods at room temperature, so refrigeration is necessary to slow any breakdown of the product