[7] Use is also contraindicated in patients with arterial bleeding
While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control
Tirzepatide is a dual-action medication known as a GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist
Persistent fatigue, brain fog, low mood, weight gain, tingling in the hands or feet, frequent illness, post-COVID fatigue, or feeling generally "off" despite eating well and sleeping enough, especially if you're vegetarian, vegan, over 50, on metformin or a long-term acid reflux medication, or have a history of low B12 or pernicious anemia
doi: 10.1002/art.21662 98 TianYTerkawiMAOnoderaTAlhasanHMatsumaeGTakahashiDet al