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Th17 cells, whose proliferation is closely connected to gut dysbiosis, produce IL-17 A and GM-CSF, which not only activate microglia but also damage the BBB by acting on endothelial IL-17RA, resulting in a self-reinforcing permeability loop

Certain molds release mycotoxins, which accumulate in the body, triggering chronic inflammation and oxidative stress

17(12): CR677CR682.

Disclose your medical history and inform the dermatologists about your allergies, liver or kidney diseases, and any medications that you are taking

In this review, various types of nanosystems (such as liposomes, polymeric nanosystems, inorganic nanoparticles and cell-derived extracellular vesicles) are designed and applied to improve the pharmacokinetics of drug formation, which could further relieve the burden on the kidneys caused by the final cumulative dose of drugs in conventional treatments